Open AccessFirst Detection of Madariaga virus in Mosquitoes Collected in a Wild Environment of Northeastern Argentina
Author(s) -
Ornela Sofía Stechina,
Griselda I. Oria,
Carolina Torres,
Adrián Díaz,
Marta Contigiani,
Marina Stein
Publication year - 2019
Publication title -
american journal of tropical medicine and hygiene
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.015
H-Index - 151
eISSN - 1476-1645
pISSN - 0002-9637
DOI - 10.4269/ajtmh.19-0475
Subject(s) - alphavirus , epizootic , biology , togaviridae , virology , outbreak , vector (molecular biology) , phylogenetic tree , virus , culex , arbovirus , alphavirus infection , transmission (telecommunications) , zoology , ecology , genetics , gene , larva , electrical engineering , engineering , recombinant dna
Madariaga virus (MADV), previously known as South American eastern equine encephalitis virus (SA EEEV; family Togaviridae, genus Alphavirus ), is a mosquito-borne virus associated mainly with equine disease. In 2010, the first human outbreak by MADV was reported in Central America, but the mosquito vectors and vertebrate hosts involved in the outbreak were not identified. In Argentina, the first epizootic of MADV was in 1930, and since then, several epizootics by MADV have been reported. However, the potential vectors and hosts involved in the transmission cycle remain unknown. In the present study, MADV was detected in Culex ( Culex ) spp. mosquitoes and the phylogenetic analysis showed that the MADV fragment amplified grouped with the lineage/subtype III of the SA EEEV complex. Our results provide information about the natural infection with MADV in mosquitoes collected in a wild environment of Argentina and its genetic relatedness.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom