Open AccessIsolation and Characterization of Mayaro Virus from a Human in Acre, Brazil
Author(s) -
Ana Carolina Bernardes Terzian,
Albert J. Auguste,
Danila Vedovello,
Marcelo U. Ferreira,
Mônica da SilvaNunes,
Márcia Aparecida Sperança,
Rodrigo Buzinaro Suzuki,
Camila Juncansen,
João Pessoa Araújo,
Scott C. Weaver,
Maurício Lacerda Nogueira
Publication year - 2014
Publication title -
american journal of tropical medicine and hygiene
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.015
H-Index - 151
eISSN - 1476-1645
pISSN - 0002-9637
DOI - 10.4269/ajtmh.14-0417
Subject(s) - chills , dengue fever , virology , isolation (microbiology) , biology , acre , incidence (geometry) , virus , genotype , medicine , microbiology and biotechnology , genetics , pathology , gene , optics , agroforestry , physics
Mayaro virus (MAYV) is widely distributed throughout South America and is the etiologic agent of Mayaro fever, an acute febrile illness often presenting with arthralgic manifestations. The true incidence of MAYV infection is likely grossly underestimated because the symptomatic presentation is very similar to that of dengue fever and other acute febrile tropical diseases. We report the complete genome sequence of a MAYV isolate detected from an Acrelândia patient presenting with fever, chills, and sweating, but with no arthralgia. Results show that this isolate belongs to genotype D and is closely related to Bolivian strains. Our results suggest that the Acre/Mayaro strain is closely related to the progenitor of these Bolivian strains that were isolated between 2002 and 2006.
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