Open AccessPrevalence of Melioidosis in Patients with Suspected Pulmonary Tuberculosis and Sputum Smear Negative for Acid-Fast Bacilli in Northeast Thailand
Author(s) -
Pornpan Suntornsut,
Kriangsak Kasemsupat,
Santi Silairatana,
Gumphol Wongsuvan,
Yaowaruk Jutrakul,
Vanaporn Wuthiekanun,
Nicholas Day,
Sharon J. Peacock,
Direk Limmathurotsakul
Publication year - 2013
Publication title -
american journal of tropical medicine and hygiene
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.015
H-Index - 151
eISSN - 1476-1645
pISSN - 0002-9637
DOI - 10.4269/ajtmh.13-0286
Subject(s) - melioidosis , sputum , acid fast , medicine , tuberculosis , pulmonary tuberculosis , bacilli , immunology , pathology , biology , bacteria , genetics
The clinical and radiological features of pulmonary melioidosis can mimic tuberculosis. We prospectively evaluated 118 patients with suspected pulmonary tuberculosis who were acid-fast bacilli (AFB) smear negative at Udon Thani Hospital, northeast Thailand. Culture of residual sputum from AFB testing was positive for Burkholderia pseudomallei in three patients (2.5%; 95% confidence interval [CI] 0.5-7.3%). We propose that in melioidosis-endemic areas, residual sputum from AFB testing should be routinely cultured for B. pseudomallei.
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