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太田 昌克1) 笠巻 祐二1) 泉 洋一2) 河村 博3) 小沢友紀雄3) 横田 廣夫4) 渡辺 一郎1) 平山 篤志1) 1)日本大学医学部内科学系循環器内科学分野 2)金沢医科大学医学部附属氷見市民病院循環器内科 3)MJG 心血管研究所 4)鉾田病院外科 Characteristics and Comparison of Cardiac Function of Natural Longevity People in the Xinjiang Uygur Autonomous Region of China and Japan Masakatsu OHTA1), Yuji KASAMAKI1), Yoichi IZUMI2), Hiroshi KAWAMURA3), Yukio OZAWA3), Hiroo YOKOTA4), Ichiro WATANABE1) and Atsushi HIRAYAMA1) 1)Division of Cardiology, Department of Internal Medicine, Nihon University School of Medicine 2)Division of Cardiology, Kanazawa Medical University, Himi Municipal Hospital 3)MJG Cardiovascular Institute 4)Department of Surgery, Hokota Hospital Background: The Uygur’s natural longevity people are found in the Xinjiang Uygur autonomous region in western China, and most of them live without any medical service or treatment. We have studied the cardiac function of Uygur’s natural longevity people and compared them with their Japanese counterparts. Subjects and Methods: We investigated 113 Uygur’s natural longevity people (UL group; average 94.8 ± 4.1 years old, 72 male and 41 female) at the Xinjiang Uygur autonomous region, China, and 56 Japanese longevity people (JL group; average 93.5 ± 3.9 years old, 11 male and 45 female) at Ibaraki prefecture, using echocardiography. Results: There were no significant differences in the left ventricle diameter and ejection fraction between the two groups (UL vs. JL = 46.6 ± 8.1 mm vs. 46.2 ± 7.4 mm, p = 0.55, UL vs. JL = 64.2 ± 9.7% vs. 66.0 ± 7.9%, p = 0.39, respectively). On the other hand, both left atrial diameter and E/e’ in the UL group were significantly smaller than those in the JL group (UL vs. JL = 32.4 ± 8.5 mm vs. 35.2 ± 7.1mm, p < 0.05, UL vs. JL = 9.3 ± 3.3 cm/s vs. 15.8 ± 5.6 cm/s, p < 0.001, respectively). Conclusions: Our results indicate that the left ventricle diastolic function of the UL group was preserved for their age compared with the JL group. These results might, at least in part, be due to racial differences, although further investigation will be necessary.