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Clinicopathologic Investigation of Surgical Site Infection in Stoma Closure Kazunari MADO1, 2), Nobuyuki KUBOTA1), Yasuhiko NAKATA1), Daijo JINNO1) and Tadatoshi TAKAYAMA2) 1)Mitsuwadai General Hospital 2)Division of Digestive Surgery, Department of Surgery, Nihon University School of Medicine Purpose: We conducted a clinicopathologic investigation of surgical site infection (SSI) after stoma closure and discuss methods for its prevention. Patients and methods: In 23 patients who underwent stoma closure at our hospital, we examined the relationship between the risk of SSI after stoma closure and various clinical factors (stoma type, interval from ostomy, operation time, intraoperative blood loss, anastomosis method, wound drainage, perioperative blood transfusion, etc.). Result: In all, 6 cases developed SSI; of these, 5 (21.7%) had incisional SSI. There were no significant differences in the clinical factors between the groups with and without SSI. There were no SSIs in the group that did not require blood transfusion or the ileostomy group, and the infection rate was low in the wound drainage group. Conclusion: Efficient wound drainage may contribute to SSI.