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【Objective】By quantifying the amount of adaptation in each stage of the prism adaptation (PA) process in patients with unilateral spatial neglect (USN) and compared with the amount obtained in normal controls, we aimed to clarify the characteristics of PA in patients with USN. We further investigated the connection of the line bisection test, which is commonly used for USN evaluation, with the amount of aftereffect. 【Materials and Methods】Subjects were 6 patients with left USN and 9 healthy volunteers. For PA, we used a 20-diopter Fresnel prism positioned at the left base of each eye and instructed the subjects to touch the targets placed at a distance of 30cm directly in front of them and at angles of 10 ° and 20 ° respectively on the left and right. The achievement error at each PA stage was measured using an open-loop pointing task. The direct effect, the adaptive effect, and the aftereffect measured at each stage were compared to the measurements at baseline, and the differences were compared to the differences obtained from the normal controls. Furthermore, we conducted a desk-based line bisection test to evaluate the improvement of neglect. 【Results】The USN patients and the normal controls only showed a significant difference in the amount of aftereffect. Although the results of the line bisection test performed during the aftereffect indicated improvement of neglect, no correlation between the amount of aftereffect and improvement of neglect was confirmed. 【Conclusion】Although the USN patients exhibited a larger aftereffect than the normal controls, no correlation between the line bisection test results and the amount of aftereffect was confirmed. Our findings suggest that the amount of aftereffect does not affect the extent of neglect improvement.

半側空間無視患者におけるプリズム順応過程の詳細