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【Purpose】To compare measurements of anterior chamber depth (ACD) obtained by anterior segment optical coherence tomography (CASIA) and an optical device for measuring axial length (IOLMaster). 【Subjects and Methods】Ninety-six eyes of 48 healthy subjects with ametropia were enrolled in this study. Their mean age was 48.0 ± 21.9 years and mean refraction was -1.8 ± 3.2 D. The IOLMaster measured axial length (AL), corneal radius of curvature (CRC), and ACD; and the CASIA measured CRC, central corneal thickness (CCT), and ACD. In 18 eyes of 9 subjects, ACD was measured in lighted and darkened rooms and under mydriasis. 【Results】The mean ACD measurements by the IOLMaster and CASIA were 3.35 ± 0.40 mm and 3.46 ± 0.39 mm, respectively. The measurement by the CASIA was significantly greater (P < 0.01) and a strong correlation was observed between both measurements (r = 0.958, P < 0.01). The mean AL was 24.49 ± 1.41 mm, and a moderate correlation with ACD was seen (the IOLMaster, r = 0.446, P < 0.01; the CASIA, r = 0.402, P < 0.01). The mean CRC values were 7.76 ± 0.26 mm by the IOLMaster and 7.78 ± 0.26 mm by the CASIA. No correlation was seen between both measurements (the IOLMaster, r = -0.36, P = 0.725; the CASIA, r = -0.39, P = 0.706). The mean ACD measurements by the IOLMaster were 3.14 ± 0.70 mm in the lighted room, 3.13 ± 0.70 mm in the darkened room, and 3.26 ± 0.68 mm under mydriasis. No statistically significant difference was seen among these measurements (P < 0.01). With the CASIA, the mean ACD measurements were 3.21 ± 0.61 mm in the lighted room, 3.25 ± 0.66 mm in the darkened room, and 3.40 ± 0.61 mm under mydriasis. No statistically significant difference was seen among these measurements (P < 0.01). 【Conclusion】Regarding ACD measurement, different devices might have different methods and principles for measurement. Therefore, we should understand the characteristics of the device when evaluating the measurement conditions and measurements.

nihon shinou kunrenshi kyoukaishi/japanese orthoptic journal

Comparison of Measurements Obtained With High-Speed Anterior Segment Swept Source Optical Coherence Tomography and an Optical Device for Measuring Axial Length in Healthy Eyes