English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background: A new microorganismidentification method using matrix-assisted laserdesorption/ionization mass spectrometry (MALDI-TOF MS) has been developed,however, reports on its use for delineating Candida spp. are scarce. Objectives: The purpose of this study was to compare the identification accuracy ofmixed infection between culture test and MALDI-TOF MS. Materialsand Methods: Eighty-nine denture wearers (average 74.0 ± 9 years) wereselected. Specimenswere immediately inoculated onto selective mediumfor CHROMagarTM Candida, and were also carried out using MALDI-TOF MS.The distribution frequencies of them were analyzed. Results: The numbersand rates of detection/non-detection by MALDI-TOF MS of genus Candida were 58/31 (65.2%/34.8%),respectively. Infection types were single infection in 34 (38.2%), mixedinfection in 24 (27.0%), and non-infection in 31 (34.8%) cases. Concerning thesingle infection, C. albicans was themost predominant (58.8%), followed by C. parapsilosis (17.6%), C. glabrata (14.7%), C. tropicalis (5.9%), and C. krusei (2.9%). As for the mixedinfection, the most frequent combination was C. albicans and C. glabrata (50.0%), followed by C. albicans and C.parapsilosis (29.2%), C. albicans and C. tropicalis (8.3%), C. glabrata and C. tropicalis (4.2%), C.albicans, C. glabrata, and C. parapsilosis (4.2%), and C. albicans, C. parapsilosis, and C.glabrata (4.2%). There were four MALDI-TOF MS positive results that were negative by theculture test. Conversely, there were six MALDI-TOF MS negative results thatwere positive by the culture test. The sensitivity and specificity of MALDI-TOFMS were 0.929 and 0.840, respectively. The concordance rate of genus Candida was 0.644, indicatingsubstantial agreement. Conclusion: Candida infection is complicated by disease type and oral cavity environment changesdue to aging. A rapid microorganism detection method, such as MALDI-TOF MS,will be helpful to quickly determine the causative pathogen in dentalinfections.

open journal of stomatology

Comparative Study of Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry and Culture Test for &amp;lt;i&amp;gt;Candida&amp;lt;/i&amp;gt; Identification