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Purpose: The evaluation of the patients with clefts; the number, type, distribution by gender, etiological factors in Aegean region in Turkey between the years 2000 to 2011. Material and Method: The patients with clefts who referred to Ege University from different cities were evaluated. The number of the clefts, the type of the clefts, and the causative etiological factors which were known, were recorded for each year separately, from 2000 to 2011. At the same time, the distribution of the gender was made for each year. Chi-square test is used for the statistical evaluation. Results: According to the results of the study, the numbers of the patients with clefts were increased day by day. Totally 741 (49.6% female, 50.4% male) patients with clefts were identified. Unilateral complete cleft lip and palate appeared in the left side was seen more in males (23.8%), while seconder palate cleft was seen more in females (16.7%). Drugs, which were used in the first trimester of the pregnancy, were the most seen etiological factors for the clefts (42.5%), while genetic was 23.3% only. Conclusion: The prevention for one of the mostly seen congenital anomaly; cleft lip and palate is still unknown. For this reason, the determination of the newborn babies with cleft lip and palate has an important role in order to give these patients more effective treatment.

The Evaluation of the Patients with Clefts in Aegean Region in Turkey between the Years 2000 to 2011