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Abrikossoff’s tumor or granular cell tumor is a rare soft and usually benign tissue neoplasm of neural origin. It occurs usually in the neck region or in the head. About 16% occur in the vulva. Some malignant cases have been reported in literature. Granular cell tumor was described first by Abrikossoff in 1926. The histogenesis of granular cell tumors is unknown. The clinical diagnosis of vulvar granular cell tumor is difficult. It may be mistaken for Bartholin gland cyst, lipoma or vulvar carcinoma when ulcerated. Histology is the mainstay of the positive diagnosis. Imagery is not essential for the diagnosis of Abrikossoff’s tumor. It is asked when the neoplasm is giant, or when there is a local recurrence or potential metastasis. Surgery is the gold standard treatment of Abrikossoff’s tumor. It consists of local excision with wide margins. Prognosis of granular cell tumor is usually good. Authors report a 25-year-old woman presented with an ulcerate tumor on the labium majus. The objective of this paper is to review the clinical and therapeutic aspects of Abrikossoff’s tumor located in the vulva from case report and literature review.

Abrikossoff’s Tumor of the Vulva, Case Report and Literature Review