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Magnesium oxide (MgO) and bismuth(III) nitrate pentahydrate as highly effective catalysts which have catalyzed the three-component reaction of cyanoacetic acid hydrazide, aldehydes and malononitrile to prepare of the corresponding N-amino-2-pyridones. These catalysts are inexpensive and easily obtained, stable and storable, easily recycled and reused for several cycles with consistent activity.

modern research in catalysis

Highly Efficient Method for Synthesis of N-Amino-2-Pyridone Derivatives in the Presence of Catalysts such as Magnesium Oxide (MgO) and Bismuth(III) Nitrate Pentahydrate (Bi(NO&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;)&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;&amp;#183;5H&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;O)