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In this paper, a high sensitive photonic crystal fiber (PCF) based surface plasmon resonance (SPR) biosensor is numerically studied. In this structure, as a plasmonic material, gold (Au) is used because of its chemical activeness. And a layer of sensing medium is used outside of the fiber to make the structure effective. Any unknown biomolecular analyte can be detected by placing or flowing it on the metal surface. Guiding properties and results are investigated using Finite element method (FEM). Results show that maximum sensitivity is 4000 nm/RIU, as well as resolution, is 2.5 × 10−5 RIU of the proposed sensor.

Numerical Analysis and Design of Photonic Crystal Fiber Based Surface Plasmon Resonance Biosensor