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Methanolic extracts of Tetracarpidium conophorum (TCME) leaf, seed or leaf + seed extract demonstrated high capacity for reversing hyperglycemia and oxidative stress comparable with the standard anti-diabetic drug, metformin, in alloxan-induced diabetic rats. The leaf + seed extracts showed the best activity among the extracts and also ameliorated oxidative stress-induced damage of pancreas and liver tissue to normal state.

journal of biomedical science and engineering

Antidiabetic and Antioxidant Effects of Methanolic Extracts of Leaf and Seed of &amp;lt;i&amp;gt;Tetracarpidium conophorum&amp;lt;/i&amp;gt; on Alloxan-Induced Diabetic Wistar Rats