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Obesity and sarcopenia combination, appropriately defined as sarcopenic obesity (SO), due to\uddisproportionally reduced/low lean body mass compared to excess fat mass, may lead to disability.\udAims: The aim of our study was to investigate the relationship among sarcopenic obesity, physical\udperformance, disability, and quality of life in a rehabilitation setting. Methods: Participants were\udrecruited among obese patients (BMI > 30 kg/m2) admitted to the rehabilitation facility at the Department\udof Experimental Medicine, Medical Physiopatology, Food Science and Endocrinology Section\udduring a 1-year period. A multidimensional evaluation was performed through bioelectrical\udimpedance analysis and anthropometry, handgrip strength test, Short Physical Performance Battery\ud(SPPB), 6-minute walk test (6MWT) and blood chemistry parameters. Psychological status\ud(SCL-90 questionnaire), quality of life, and comorbidity (Charlson comorbidity index score) were\udalso evaluated. Obesity was diagnosed as increased fat mass by 35% in women and by 25% in men.\udSarcopenia was defined if lean body mass (LBM) was <90% of the subject’s ideal LBM. Results: 79\udpatients (48 women and 31 men; mean age: 60.1 ± 11.5 years, and 58.6 ± 10.8 years, respectively)\udwere enrolled. Results showed a high prevalence of SO (54.4%) in our samples of obese subjects.\udSarcopenia was present not only among older obese adults but also among younger obese subjects,\udand was related to reduced functional performance, to inflammatory status and to worse psychological\udstatus and quality of life

Sarcopenic Obesity: Correlation with Clinical, Functional, and Psychological Status in a Rehabilitation Setting