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The half generation Poly(amidoamine) (PAMAM) dendrimers was synthesized and characterized and modification by heterocyclic DNA base (Cytosine) . The conjugated Cytosine  modified detected by FT-IR, 1H NMR, 13C NMR and Mass spectroscopy analysis.

The Modification of Poly amidoamine (PAMAM-G0.5) by Cytosine