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The experiment was conducted to evaluate the acutetoxicity of aqueous extract of Adenium obesum stem bark in juveniles of Clariasgariepinus by assessing the hematological responses of the exposed groupscompared to the control in a static non-renewal bioassay for 96 hours. Thefishes (N = 180, mean weight and length 21.48 ± 3.32 g and 11.37 ± 1.23cm) respectively were randomly distributed 10 (ten) fishes per group intriplicates constituting six experimental groups as follows; G1 (Control), G2(6.5 mg/l), G3 (7.8 mg/l), G4 (8.5 mg/l), G5 (9.5 mg/l) and G6 (11.5 mg/l). Red blood cell (RBC) count, packed cellvolume (PCV) and hemoglobin concentration were decreased significantly (P Adeniumobesum stem bark is toxic to erythrocytes while a converse adaptiveresponse in the white blood cells.

advances in biological chemistry

Physico-Chemical Evaluation and Hematological Responses in &amp;lt;i&amp;gt;Clarias gariepinus&amp;lt;/i&amp;gt; (Burchell 1822) Juveniles Exposed to &amp;lt;i&amp;gt;Adenium obesum&amp;lt;/i&amp;gt; Stem Bark Acute Bioassay