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We developed a novel PCR method aimed at identi- fying and amplifying native codon sequences of muta- tion-prone amino acids in DNA gyrase implicated in quinolone resistance using a naturally occurring co- don bias in <i>E. coli</i> DNA gyrase A

advances in biological chemistry

Use of a naturally occurring codon bias for identifying topoisomerase mutations in ciprofloxacin resistant &amp;lt;i&amp;gt;Escherichia coli&amp;lt;/i&amp;gt; using PCR and future prospects with other bacterial genera: A pilot study