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Antimicrobial resistance due to production of extended-spectrum ß-lactamases by Escherichia coli and Klebsiella species (ESBL-EK) is concerning. Previous studies have shown that bacteremia due to ESBL-producing organisms is associated with increases in length of stay and/or mortality rate. Rates of infection by ESBL-EK vary worldwide, and regional differences in the prevalence of risk factors are likely. Few Canadian studies assessing risk factors for ESBL-EK infections or the outcomes of empiric therapy have been published.

canadian journal of hospital pharmacy/the canadian journal of hospital pharmacy

Risk Factors for and Outcomes of Bacteremia Caused by Extended-Spectrum ß-Lactamase– Producing Escherichia coli and Klebsiella Species at a Canadian Tertiary Care Hospital