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Reversibility of obstructive lung disease is traditionally defined by changes in FEV 1 or FVC in response to bronchodilators. These may not fully reflect changes due to a reduction in hyperinflation or air-trapping, which have important clinical implications. To date, only a handful of studies have examined bronchodilators' effect on lung volumes. The authors sought to better characterize the response of residual volume and total lung capacity to bronchodilators.

Residual Volume and Total Lung Capacity to Assess Reversibility in Obstructive Lung Disease