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The F(IO(2)) for a nasal cannula with constant flow (CF) depends on the anatomic reservoir (AR), which is affected by changes in frequency and end-expiratory flow. Conversely, pulse flow (PF) devices do not require the AR. The purpose of this study was to compare the F(IO(2)) delivered by a nasal cannula supplied by CF via oxygen tank with that delivered by PF delivered via portable oxygen concentrator. Hypotheses were (1) a lung model of COPD with non-zero end-expiratory flow decreases F(IO(2)) for CF more than for PF, and (2) CF and PF perform differently in terms of F(IO(2)) delivery, despite having equivalent settings.

Effect of the Anatomic Reservoir on Low-Flow Oxygen Delivery Via Nasal Cannula: Constant Flow Versus Pulse Flow With Portable Oxygen Concentrator