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Objective: To assess how the modulation transfer function (MTF) was influenced by the k-space trajectory with partial Fourier fractions in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), calculating MTF using computer simulations. Methods: Reference data for signal intensity were acquired using breast model at different concentrations and used to create a digital phantom. Frequency images were created by fast Fourier transform, divided into parts, and a new image formed by taking one part from each. The MTFs were then calculated. Three linear signal intensity slope models (low, medium, and high) and three exponential curve models (slow, medium, and rapid) were created using the reference data. Results: The smaller the partial Fourier fraction used, the faster the decline in MTF. The MTF of the three linear slope models showed that the higher gradient of the slope used, the more rapid was the decline in MTF. The MTF of all three exponential curve models were more gradually decreasing than all three linear slope models. Conclusion: The MTF was influenced by the k-space trajectory with partial Fourier fractions in DCE-MRI using computer simulations. The reverse linear order was found to be less influenced than the linear order by the partial Fourier fraction.

journal of computer science and systems biology

Comparison between Linear and Reverse Linear K-Space Order with Partial Fourier Fractions for Modulation Transfer Function in Dynamic Contrast-Enhanced Magnetic Resonance Imaging: A Simulation Study