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Background: The search for an agent that would predictably and permanently occlude the tubules, and blend with them led to the discovery of HYDROXYAPATITE (HAP). The present double blinded randomsed controlled clinical trial aimed to compare the desensitizing effects of two forms of HAP with 2 other popular agents, potassium nitrate and potassium nitrate with sodium monofluorophosphate. Methods: Clinical study: 716 hypersensitive teeth in 50 patients with hypersensitive symptoms, confirmed by visual analogue scale (VAS) and verbal rating scale (VRS), were randomly divided into 4 groups (A,B,C and D) treated with HAP dry sol gel and liquid precipitate form, potassium nitrate and sodium monofluorophosphate respectively. The responses were evaluated at 0, 1 day, 1, 2, 4 and 8 weeks respectively for all groups and later statistically analysed. Results: HAP treated teeth showed statistically significant reduction in hypersensitive symptoms (p<0.001) requiring fewer applications compared to other groups at the end of 1st day, 2 and 8 weeks respectively. At the end of 8 weeks, all 4 groups showed significant change from baseline scores (p<0.001). Conclusion: HAP showed definite potential as an effective permanent desensitizer when compared to potassium nitrate and sodium monofluorophosphate when used as an in-office procedure. However, its efficacy when used as part of dentifrice like the other 2 agents needs further research.

journal of oral hygiene and health

Comparative Evaluation of Hydroxyapatite, Potassium Nitrate and Sodium Monofluorophosphate as in Office Desensitising Agents–A Double Blinded Randomized Controlled Clinical Trial