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Thrombophilia is an important medical problem that carries a great morbidity and mortality especially in young patients and great laboratory workup is usually needed to detect the underlying etiology. Several factors have been claimed to be responsible for thrombosis, some of them are common and others are not, the acquired causes represent the majority while hereditary causes are the minority. The case is an example for acute thrombosis in hepatic veins and chronic thrombosis in portal vein in a young adult that was addict for tramadol for last three years with excellent response to anticoagulation as regards hepatic vein thrombosis.

Combined Hepatic and Portal Vein Thrombosis due to Uncommon Hereditary Factors for Thrombophilia in Young Adult