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In the 1950s, three groups made it their goal to determine the structure of DNA. The first group to start was at King's College London and was led by Maurice Wilkins and was later joined by Rosalind Franklin. Another group consisting of Francis Crick and James D. Watson was at Cambridge. A third group was at Caltech and was led by Linus Pauling. We have recently celebrated 60 years from the pioneering discovery of the Double Helix Structure (1953) announcing a series of articles in last year’s editorial of this Journal. In 2003, coinciding with the 50thanniversary of this momentous achievement in biology and the description of the DNA double helix was also the year that NHGRI celebrated the historic culmination of one of the most important scientific projects in history: the sequencing of the human genome.

molecular biology

Celebrating 30 Years since the Conception of the Human Genome Project (HGP): New Concepts Ahead-Molecular Biology Tools to Efficiently Modify the HG and/or Other Species-Genomes-Implications for Health and Disease