English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Diabetes is a disease in which premature development of conditions which increase blood coagulation are the leading cause of death. A reduction in the consequences of elevated glucose levels is the main focus of clinical treatment. It has been determined that the addition of glucose to anti-coagulated human blood, followed by incubation for 24 hours results in the generation of a hypercoagulable state, which is evaluated by reduction in whole blood clotting time. Incubation for 2 hours did not show the same change in clotting. Furthermore, the addition of glucono-delta-lactone, a low-toxicity food additive mitigated the hypercoagulable state which may, in part, be produced by tissue factor generated by up-regulated monocytes. This demonstration of in vitro glucose toxicity may broaden our clinical knowledge of the diabetic state. Also, glucono-delta-lactone warrants additional studies to confirm its anticoagulant properties.

Glucono-Delta-Lactone: An In Vitro Inhibitor of Hyperglycemia-Induced Coagulation