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Purpose: To compare the pullout loads of variable versus fixed angle screws in anterior lumbar interbody fusion (ALIF) plate/screw constructs in both foam and cadaveric models. Methods: An ALIF plate was secured to a 0.160 g/cm3 polyurethane foam block (N = 10) with fixed or equivalently positioned variable angle screws and pulled out at 1 mm/min to failure. Embalmed human vertebral pairs (N = 10) were similarly utilized to compare fixed versus variable angle plate/screw constructs for pullout strength. Results: There was no statistically significant difference between fixed and variable angle plates for either foam (p = 0.6) or vertebral specimens (p = 0.3) based on maximum load or stiffness. The maximum load for the vertebral specimens was on average 39% of that for the foam (p = 0.001) and the stiffness was about 55% of that for the foam (p = 0.001). Conclusions: In this study, no statistically significant difference in pullout strength or stiffness was found between fixed and variable angle ALIF plate/screw constructs. However, the embalmed cadaveric bone model was shown to be statistically weaker in pullout strength and stiffness when compared to the foam model. This study suggests that the foam model may not always be representative of the cadaveric model in the magnitude of load, but may still provide good comparative results between different designs.

Pullout Strength Of Anterior Lumbar Interbody Fusion Plates: Fixed Versus Variable Angle Screw Designs