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Eurycoma longifolia is traditionally known for its adaptogenic properties and often used for the general well-being and increased performance in daily life. Methods: In a randomized, double blind, placebo-controlled clinical trial, 40 Malaysian men aged 30-55 years performed a battery of physical testings during which the ratio of Testosterone (T) to Epitestosterone (E) was analyzed. The daily intake was 300 mg of the freeze-dried water extract of Eurycoma longifolia root (Physta®, Biotropics Malaysia) or placebo for a period of 12 weeks. Results: At the end of the study the T/E-ratio in the herbal group ranged from 0.03 to 2.95 and was not significantly different from values at baseline (p=0.49). Further, the ratio-values for E. longifolia compared to placebo did not change over time. The weight lifting force which measures muscular strength using back & leg strength test, increased significantly from baseline to end of the study in the herbal group by approximately 14 kg (p=0.0166). Conclusion: The ratios of testosterone to epitestosterone did not change during a 12-weeks E. longifolia intake. The data suggest that this herb does not exhibit “doping”- like effects. Instead, muscular strength improved significantly in the back and leg with E. longifolia supplementation rendering this herb good for physical performance minus the doping effects.

The Eurycoma Longifolia Freeze-Dried Water Extract-Physta Does not Change Normal Ratios of Testosterone to Epitestosterone in Healthy Males