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A reduction in the blood pressure levels triggers, among other responses, a signaling cascade mainly controlled by the kidneys; this event is responsible for reestablishing the blood pressure, being known as renin, angiotensin, and aldosterone system – RAAS. The aldosterone, the last hormone released in this cascade, displays several effects in its target tissue such as kidneys, colon, brain, and cardiovascular system [1]; however, high levels of aldosterone, in certain diseases, lead to deleterious effects in most of these organs. In the next lines, our focus will be the on the cardiac tissue.

Antagonists of the Mineralocorticoid Receptor or A New Pharmacological Class?