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Role of Nanotechnology in Cancer Diagnostics
Author(s) -
Giuseppe Toffoli
Publication year - 2013
Publication title -
journal of carcinogenesis and mutagenesis
Language(s) - English
Resource type - Journals
ISSN - 2157-2518
DOI - 10.4172/2157-2518.1000135
Subject(s) - ovarian cancer , breast cancer , cancer , disease , computational biology , bioinformatics , medicine , biology , pathology
Copyright: © 2013 Toffoli G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Cancer is a high heterogeneous disease difficult to understand and cure. Many historically classified tumors are now being revisited in order to better define the therapeutic strategy [1]. For example, the recent molecular classification of breast and ovarian cancers suggests a different pathological taxonomy to highlight the similarity with other types of cancers that originate from different organs [2]. On the other hand, detailed knowledge of the mechanisms behind the tumors can offer common clinical solutions for what is now a different pathology. The Cancer Genome Atlas Research Network (CGARN) has defined at molecular level a high similarity between basal like breast cancer and serious ovarian cancer which includes widespread genomic instability, gene alterations, and mRNA expression implying common biomarkers and therapeutic targets [3].

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