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Herein we report a case of 46-year-old male patient who was presented with chest pain and dyspnea and was diagnosed with sub-massive pulmonary embolism (PE) and intra-cardiac bi-atrial thrombus, echocardiography showed decreased right ventricular systolic function. Following treatment with 100 mg tissue plasminogen activator (tPA), the patient reported clinical improvement, in addition to improved ventricular function as assessed by echocardiography. In the present report, we describe a case of sub-massive PE with intra-cardiac bi-atrial thrombus successfully managed with thrombolytic treatment without occurrence of adverse events.

Sub-Massive Pulmonary Embolism with Large Intra-Cardiac Bi-Atrial Thrombi Successfully Treated with Systemic Thrombolytic Therapy