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these evidences doesn’t exclude the differential efficacy of probiotics in human subjects, hence very well controlled/ designed studies are urgently needed to check the efficacy of probiotics in human health against obesity and diabetes. A deeper knowledge of our gut ecology will be mandatory in the hope to target much more specific probiotic intervention. In this regards it is of interest the recent intriguing review from Rastmanesh [13] suggesting that a high-polyphenol and selectively-restricted probiotic diet could represent a novel strategy for planning a successful dietary regimen and/or neutraceutical/ pharmaceutical preparations to achieve and maintain a normal body weight in obese individuals. Overall, such studies will also give opportunities to industries to think about the risk vs safety of probiotic formulations for obesity and diabetes in consumers, worldwide.

Probiotics Mediated Modulation of Gut-Flora Might Be a Biotherapeutical Approach for Obesity and Type 2 Diabetes