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Chagas disease is caused by the parasite Trypanosoma cruzi, is endemic in Latin America and leads to an estimated 14,000 deaths per year and around 100 million people at risk of infection. Drugs currently used in the treatment of Chagas are old, partially effective and have numerous side effects.

Novel 3-Nitro-1 H -1,2,4-Triazole-Based Compounds as Potential Anti-Chagasic Drugs: In Vivo Studies