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Transient receptor potential (TRP) channels expression is enhanced significantly in colon cancer cells and  Low Lever Laser Treatment (LLLT), is known to have effects and is used clinically in the treatment ofmany diseases, including colon cancer. We aimed to reveal the effects of (LLLT) on apoptosis of colon cancer and on the efficacy of cyclophosphamide via Transient receptor potential melastatin 2 (TRPM2) channels.

LLLT enhance cyclophosphamide induced TRPM2 channel activation in human colon cancer cells