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We evaluated the efficacy and safety of avelumab, an anti-PD-L1 antibody, in patients with metastatic or unresectable colorectal cancer (mCRC) with mismatch repair deficiency (dMMR)/microsatellite instability-high (MSI-H) or POLE mutations.

cancer research and treatment/cancer research and treatment

A Phase II Study of Avelumab Monotherapy in Patients with Mismatch Repair-Deficient/Microsatellite Instability-High or &lt;i&gt;POLE&lt;/i&gt;-Mutated Metastatic or Unresectable Colorectal Cancer