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Multi-component reactions are very popular because they offer a wealth of products, while requiring only a minimum effort\udcombining many elements of an ideal synthesis, such as operational simplicity, atom economy, bond-forming efficiency, and the access\udto molecular complexity from simple starting materials. As such, multi-component reactions have become the cornerstones of both\udcombinatorial chemistry and diversity-oriented synthesis and thus playing a central role in the development of modern synthetic methodology\udfor pharmaceutical and drug discovery research. In this Insight we will highlight the development of novel multi-component\udreactions based on the reactivity of carbodiimides, paying particular attention on their mechanistic features. We will address our attention\udon the process developed by us and others groups, in these last years, for the synthesis of biologically relevant structures such as,\udfor example, heterocycles and glyco-conjugates

Carbodiimides-Mediated Multi Component Synthesis of Biologically Relevant Structures