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Oral health is a part of general health that should not be separated from mental health. Oral health research in psychiatric patients shows that mental disorders and the use of such drug therapy as antipsychotic drugs can escalate the prevalence and severity of oral diseases. The objective of this study to examine the effect of antipsychotic medication by using duration toward the salivary flow rate of schizophrenics in the Special Hospital of South Sulawesi Province. This research is an analytical observation with Cross-Sectional study design. The 74 sample patients was obtained from nonprobability sampling method. The study was conducted at Dadi Special Hospital of South Sulawesi. The obtained data were analyzed by linear regression test and processed using the SPSS application 23.0 version (SPSS Inc., Chicago, IL, USA). The duration of drug use had a significant impact on the salivary flow rate of schizophrenics (p < 0.05). Based on the F test, the value of the F statistic was obtained 8.851 with the number of significanceprobability 0.004, and the coefficient value of determination is 0.109. There is a duration effect of antipsychotic drug use on the decreasing of the salivary flow rate of schizophrenics significantly as the side effect of antipsychotic drug use.

The Effect of Duration of Antipsychotics Medicine Use Toward The Salivary Flow Rate of Schizophrenics In Special Hospital of South Sulawesi Province