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Breast cancer incidence tends to increase, and it is suggested that it largely contributes to the rise of newly diagnosed cancers among young patients. The aim of this study to determine breast cancer immunohistochemistry features among young women in West Sumatera Indonesia. This study analyzed medical records of patients who belonged to the national health insurance program with breast cancer treatment. The study was conducted at the Dr. M. Djamil General Hospital Padang. The population in this study are all breast cancer patients (1st January 2005 to 19th October 2018). Amount of breast cancer among young women is 88 patients. Data were collected from medical records at the Division of Surgical Oncology Dr. M. Djamil General Hospital in Padang. Univariate analysis of the data in this study was used to find the disease-free and overall survival with subtype and stage and bivariate analysis was conducted on these survival statistics using the Kaplan-Meier method and log-rank test. Immunohistochemistry characteristics among young women with breast cancer using chi-square test. Data were analyzed by using STATA program. A two-tailed P-value of <0.05 was considered statistically significant. Data were analyzed using the Stata version 14.2 (Stata Corporation). The results showed LVI, stage, KI67, subtype, and status is associated with survival breast cancer among young women in West Sumatera, Indonesia (p<0.05). There is related breast cancer subtype significantly with the survival of breast cancer patients based on disease-free survival (HR = 1.07 (95% CI 0.62-1.83)) with p log-rank test ≤ 0.05. But overall survival did not result in a statistically significant (HR = 0.99 (95% CI 0.58-1.70)) with p log rank test > 0.05. There is related significantly breast cancer subtype with the survival of breast cancer patients based on disease-free survival (HR = 1.07 (95% CI 0.62-1.83)) with p logrank test ≤ 0.05. But overall survival did not result in a statistically significant (HR = 0.99 (95% CI 0.58-1.70)) with p log-rank test > 0.05. This analysis confirmed LVI, stage, KI67, subtype and status is associated with survival breast cancer among young women in West Sumatera, Indonesia.

Breast Cancer Immunohistochemistry Features Among Young Women in West Sumatera, Indonesia