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Sir, Several cook‐up techniques exist for psychoactive substance users. Opioid and cocaine are two common psychoactive substances where cook‐up techniques are most frequently used. Although recent reports have documented purposive use of lemon juice among crack cocaine users with its adverse effects (e.g., candidal endophthalmitis and disseminated candidiasis), reports of the use of the same in opioid dependence are sparse.[1‐6]

Intravenous Use of Lemon Juice with Brown Sugar: A Potentially Fatal Cook-Up Technique?