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Endometrial pathologies contribute to a large proportion of abnormal uterine bleeding (AUB) during the reproductive years as well as after menopause. These pathologies can vary from variants of normal endometrium to benign, premalignant and malignant causes. Invasive sampling and subjecting it to histological diagnosis is the only confirmatory way to differentiate these causes, direct treatment and prognosticate the pathologies of the endometrium. Currently, there is a lack of highly efficacious clinically available noninvasive tests or biomarkers to differentiate these.[1] Endometrial thickness seen during transvaginal sonography (TVS) is the only parameter popularly used to define endometrial pathologies, which miserably fails to diagnose specific lesions of the endometrium.[2-4]

gynecology and minimally invasive therapy

A novel non invasive screening tool for triaging endometrial pathologies in abnormal uterine bleeding: Diseases of endometrium – evaluation and risk scoring