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We read with great interest the article of Oh et al.[1] about the use of macroscopic on-site evaluation (MOSE) as an adjunct technique in EUS guided fine-needle biopsy (FNB). The authors reported that MOSE can improve the diagnostic accuracy of FNB samples of up to 94.5%. Due to the limited availability of rapid-onset site evaluation (ROSE), they argued that EUS-guided FNB with MOSE can replace EUS-FNA with ROSE in terms of optimal histological obtaining and diagnostic accuracy. However, the direct comparison of the two techniques was not previously reported.

endoscopic ultrasound

Macroscopic on-site evaluation during EUS-fine needle biopsy with combined cyto and histological analysis may overcome the need of rapid on-site evaluation