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Aims and Objectives: Adverse drug reaction (ADR) may infringe upon compliance, which compromises therapy outcomes in chronic diseases. Our study focused on pharmacovigilance in stigmatizing disease vitiligo, concern with improving disease management incorporating current medical knowledge. Materials and Methods: Therapies in 250 vitiligo cases were scrutinized over period of six months, examining consistency to consensus approach and profiling of the adverse effects. Results: Adverse drug effects occurred in fifth of localized and third of generalized vitiligo patients. Adherence to consensus line of therapy resulted significantly in less adverse effect incidence, and steroid overtreatment was major determinant of risk. Conclusion: Consistency of treatment to consensus approach based on disease extent is prudent to reduce adverse drug effects in vitiligo. Increased vigilance, due psycho-social address, and incorporation of safe and efficacious new immunomodulator drugs is emphasized for consideration toward improved current vitiligo management.

Pharmacovigilance of conventional therapy in 250 cases of vitiligo at tertiary specialty care