English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Territorial middle cerebral artery (MCA) infarcts are among the most devastating forms of ischemic cerebral disease.[5] It is associated with life‐threatening cytotoxic edema, with mortality reported as high as 80%.[1] Patients suffering intractable intracranial hypertension secondary to malignant edema often undergo hemicraniecomty as a life‐preserving measure. The efficacy of hemicraniectomy in this context is now documented by several randomized controlled studies (RCTs). The controversy that remains involves the functional status of the surviving patient, since territorial MCA infarcts are intrinsically associated with significant disability. Here we review the available RCT data, with the goal of addressing this controversy.

Hemicraniectomy in the management of malignant middle cerebral artery infarction: Lessons from randomized, controlled trials