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Interleukin-1 (IL-1) is one of the pro-inflammatory cytokines that plays a main role in the regulation of immune and inflammatory responses. Interleukin 4 (IL-4) as an anti-inflammatory cytokine regulates balance between Th1 and Th2 immune responses. this study was undertaken to investigate the IL-1β and IL-4 genes polymorphisms in patients with systemic lupus erythematosus (SLE) and also association between the polymorphisms and susceptibility to SLE.

indian journal of medical research

Interleukin-1β (IL-1β) &amp; IL-4 gene polymorphisms in patients with systemic lupus erythematosus (SLE) &amp; their association with susceptibility to SLE