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To the Editor: Sevoflurane and desflurane are the most common general anesthetics used in children. Previous study has shown that these agents can affect the electrocardiogram (ECG) markers,[1] leading to fatal ventricular arrhythmia. The followings were identified as useful indices for predicting and estimating the occurrence of a fatal arrhythmia: the interval between the peak and the end of T wave (Tp‐Te),[2] the ratio of the Tp‐Te interval to the QT interval ([Tp‐Te/QT][3]), and the JT interval (JT), which is measured from the end of the QRS complex to Te.[4] The QT interval may be affected by sex and age.[5] However, little is known about the co‐effect of the inhaled agent and sex on the corrected QT (QTc) and Tp‐Te/QT and Tp‐Te/JT ratios.

Inhalation of Sevoflurane and Desflurane Can Not Affect QT Interval, Corrected QT, Tp-Te/QT or Tp-Te/JT in Children