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Adolescent idiopathic scoliosis (AIS) is one of the most prevalent diseases among teenagers, with an incidence rate of 1–3% worldwide, and at least 0.02% of patients require surgical treatment.[1] The “gold standard” procedure is instrumentation and fusion of 10 or more vertebrae with forceful correction of the deformity.[2] Although autogenous bone grafts are the “gold standard” for spine fusion,[3] significant progress has been made in discovering bone graft alternatives, including freeze‐dried allograft, demineralized bone matrix (DBM), triosite ceramics, and bone marrow aspirate (BMA), which have been used as substitutes for iliac crest in AIS surgery.[4‐7] Results show that these substitutes could gain similar benefits for spine fusion, while other evidences fail to be replicated. Orthopedic surgeons are put into a dilemma of which substitute is the best for AIS surgery with less complications while achieving higher fusion rate. In this article, we presented our viewpoint on this issue.

Bone Graft Options for Spine Fusion in Adolescent Patients with Idiopathic Scoliosis