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Extra-pulmonary tuberculosis (EPTB), caused by  Mycobacterium tuberculosis , is the leading cause of communicable disease-related deaths in people with human immunodeficiency virus (HIV) worldwide and in South Africa.  Mycobacterium tuberculosis  disseminates haematogenously from an active primary lung focus and may affect extra-pulmonary sites in up to 15% of patients. Extra-pulmonary TB may present with a normal chest radiograph, which often causes a significant diagnostic dilemma. This review describes the main sites of involvement in EPTB, which is illustrated by local imaging examples.

The silent pandemic in South Africa: Extra-pulmonary tuberculosis from head to heel