Open AccessFace of the giant panda sign in Wilson disease
Author(s) -
Sumit Chakraborty,
Sumantro Mondal,
Debanjali Sinha,
Arijit Nag
Publication year - 2013
Publication title -
south african journal of radiology
Language(s) - English
Resource type - Journals
eISSN - 2078-6778
pISSN - 1027-202X
DOI - 10.4102/sajr.v17i3.276
Subject(s) - pathognomonic , medicine , magnetic resonance imaging , sign (mathematics) , radiology , midbrain , disease , neuroradiology , pathology , neurology , central nervous system , mathematical analysis , mathematics , psychiatry
Wilson disease usually presents with neurologic or hepatic manifestations. Magnetic resonance imaging (MRI) of the brain is very informative in diagnosiing of this disease, especially in patients with neurological features. High T2 signal intensity in the corpus striatum is the most commonly encountered MRI finding. The 'face of the giant panda' sign is seen on axial T2-weighted MRI, and results from abnormal signal intensities in the midbrain. Though uncommon, the sign is considered as the pathognomonic MRI sign of Wilson disease
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