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Background  Pregnancy can be associated with anxiety symptoms because of anticipated uncertainty.    Aim  This study investigated pregnancy-related anxiety symptoms (PRASs) and their associated factors amongst pregnant women.    Setting  Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria.    Methods  This cross-sectional survey involved 230 pregnant women attending antenatal clinic at a tertiary teaching hospital in Nigeria. Pregnancy-related anxiety symptoms, maternal worries, personality traits and social support were measured by using Perinatal Anxiety Screening Scale (PASS), Cambridge Worry Scale (CWS), Big Five Personality Inventory (BFI-10) and Maternal Social Support Scale (MSSS) respectively. Socio-demographic and obstetric details were also obtained. The Chi-square, t-test and logistic regression were used.    Results  Respondents’ mean age was 28.2 ± 5.4 years, whilst 192 (83.5%) were of Yoruba ethnicity. Twenty-four respondents (10.4%) were in the first trimester, 85 (37.0%) in the second and 121 (52.6%) in the third trimester. Some 154 (67.0%) were parous. The prevalence of PRAS and major maternal worries were 43.5% and 55.7% respectively. The socio-demographic factors significantly associated with PRAS were age ( p  = 0.004), ethnicity ( p  = 0.001), educational level ( p  = 0.011) and living arrangement ( p  = 0.029). Associated obstetric factors include trimester ( p  = 0.01), hypertension ( p  = 0.006), past miscarriage(s) ( p  = 0.013) and past pregnancy complication ( p  = 0.030). Significant psychosocial factors were partner social support ( p  = 0.038), maternal worries ( p  < 0.001) and extraversion ( p  = 0.016). Factors that contributed significantly to regression models were older maternal age and socio-medical worries.    Conclusion  High level of PRAS and major maternal worries were common amongst antenatal clinic attendees of a tertiary teaching hospital in Nigeria. Older maternal age and socio-medical maternal worries are important predictors of PRAS.

Pregnancy-related anxiety symptoms and associated factors amongst pregnant women attending a tertiary hospital in south-west Nigeria