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Background  Reflecting on progress and challenges in meeting global human immunodeficiency virus (HIV) targets is often done ahead of World AIDS Day. This article reflects on progress and the continuing challenges in meeting targets in South Africa (SA).    Objective  To review policy and implementation related progress and continuing challenges towards eliminating HIV as a public health threat by 2030.    Method  Policy analysis and review of modeling data from Thembisa 4.3.    Results  South Africa has made significant progress in the adoption of policies with two exceptions. While there are gaps in reaching the 90-90-90 implementation targets, progress has been made in the past decade.    Conclusion  While progress has been made in the past decade towards the global targets, much work remains to ensure that HIV transmission is curtailed and those that require treatment are initiated on treatment and are virally suppressed.

World AIDS Day 2020: Reflections on global and South African progress and continuing challenges