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A 75-g oral glucose tolerance test (OGTT) is a sensitive test in most populations for diagnosis of type 2 diabetes mellitus (T2DM) and commonly used to identify high-risk individuals of T2DM [1]. The diagnostic criteria define diabetes as a fasting glucose ≥126 mg/dL or a 2-hour glucose challenge ≥200 mg/dL, but not including 1-hour glucose level. Recently, data obtained in population studies have suggested that 1-hour glucose level after OGTT can provide a better predictor for development of T2DM than fasting or 2-hour glucose [2]. And, subjects with 1-hour glucose levels of ≥155 mg/dL with normal glucose tolerance (NGT 1-hour high) have been considered as high risk of T2DM [3], which were more insulin-resistant and worse β-cell function than subjects with NGT 1 hour-low (u003c155 mg/dL) [4].

diabetes and metabolism journal

Response: Normal Glucose Tolerance with a High 1-Hour Postload Plasma Glucose Level Exhibits Decreased β-Cell Function Similar to Impaired Glucose Tolerance (<i>Diabetes Metab J</i>2015;39:147-53)

Response: Normal Glucose Tolerance with a High 1-Hour Postload Plasma Glucose Level Exhibits Decreased β-Cell Function Similar to Impaired Glucose Tolerance (Diabetes Metab J2015;39:147-53)